EVALUATION OF ANTIBACTERIAL ACTIVITY OF SOME MEDICINAL PLANTS BY BIOAUTOGRAPHY
- Publish Date: 2 - September - 2021
Research Abstract:
This study aimed to qualitatively identify the bioactive compounds in Acacia cyanophylla, Phlomis syriaca, and Scolymus hispanicus using Thin Layer Chromatography (TLC), and to evaluate their antibacterial activity against Escherichia coli infection isolates. The results confirmed the presence of flavonoids, saponins, bitter principles, and essential oils in all three plants. Both aqueous and ethanolic extracts exhibited antibacterial activity, with the ethanolic extract of Acacia cyanophylla showing the strongest effect, reflected by the lowest MIC values. Bioautography analysis indicated that flavonoids were the main compounds responsible for the antibacterial activity. These findings suggest that Acacia cyanophylla is a promising natural source of antibacterial agents and may contribute to the development of plant-based therapeutic applications in the future.
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